Periodic Labs builds AI scientists and autonomous laboratories that synthesize materials, characterize properties, and generate experimental data for physical sciences including physics and chemistry. The company deploys custom AI agents to help semiconductor manufacturers analyze experimental data for applications such as heat dissipation. Their technology combines AI models that form hypotheses, run quantum mechanical simulations, and plan syntheses with robotic lab systems that execute experiments autonomously, incorporating reinforcement learning where physical reality provides feedback. Periodic Labs was co-founded in 2025 by Liam Fedus, former head of post-training at OpenAI and co-creator of ChatGPT, and Ekin Dogus Cubuk, former chemistry and physics research lead at Google DeepMind who co-authored the GNoME paper. The founding team comprises experts including Abhijeet Gangan, Alexandre Passos, and others from OpenAI, DeepMind, and Meta. The startup raised a $300 million founding round led by Andreessen Horowitz with Felicis, DST Global, NVentures, Accel, and individuals including Jeff Bezos, Eric Schmidt, Elad Gil, and Jeff Dean. Headquarters are in Menlo Park, California.