Topology Ventures is an early-stage venture capital firm based in San Francisco that invests in frontier technologies. The firm focuses on areas including AI, decentralized networks, neurotechnology, aerospace, and robotics. It deploys capital into seed and early-stage startups developing technologies in these domains. Casey Caruso serves as the founder and solo general partner. The debut fund closed at $75 million in 2024. Backers include Marc Andreessen, an OpenAI cofounder, and Paris Hilton. The firm targets companies advancing hardware-software intersections in high-risk, high-reward sectors.